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What is Propecia?

Propecia (generic name Finasteride) is a drug used for the treatment of male pattern baldness and, under the Proscar brand, enlarged prostates. Propecia is produced by the pharmaceutical company Merck. It is the biggest brand for the drug named finasteride but there are other generic brand names for this compound. Click here forĀ Uk buyers of finasteride and for other buyers continue below.To Buy propecia, you need a prescription , but that can be arranged by some online pharmacies.

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How does Propecia work to treat male pattern baldness?

Propecia's main ingredient is a chemical that inhibits the enzyme type II 5a-reductase. This enzyme converts the male sex hormone testosterone into dihydrodeoxycorticosterone (DHT). Male pattern baldness occurs when there is too much DHT in the scalp. Normal hair production and maintenance processes are disrupted, and the scalp slows down hair production or, in many cases, stops production altogether. The culprit, in this process, is DHT. Finasteride (Propecia) helps increase the scalp's hair levels or reduces hair loss by actively blocking the production of DHT.

Benefits of Propecia.

Through the years, there have been some inconsistencies in the way Propecia has been related to prostate cancer. It seems, though, that the latter studies have proven that the drug can bring more benefits than problems.See more on the effectiveness and benefits of propecia

Effectiveness of the Drug, Propecia.

Propecia looks to be a really effective drug if you consider the remarkable difference between the results experienced by the control group compared to the ones experienced by the test group.
Are the results of the drug permanent or temporary, though?

According to studies, Finasteride is only effective as long as the patient continues to take it. If you decide to stop using Propecia, you may again experience hair loss after about six months to a year. Unfortunately, you will also lose the hair that you have gained during the active treatment period, and hair loss is again reactivated.
If you do make use of Propecia, you will experience that it is most effective on particular parts of your scalp. You will find the best hair growth on the crown of your head, though the medication is really designed to restore hair and stop hair loss not only at the crown areas, but also at the hairline.

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How does Finasteride block DHT production?

The male sex hormone testosterone is produced mostly in the male's testes and adrenal glands. Testosterone binds to a liver-produced protein called SHBG (sex hormone-binding globulin). By preventing testosterone from being metabolized by the body, SHBG enables testosterone to be transported to the body's cells. In certain parts of the male body, primarily the prostate, skin, and scalp, testosterone is turned into a more potent form called 5a-dihydrotestosterone (DHT). This conversion is made possible by 5a-reductase, an enzyme. DHT is an amplified and more powerful version of testosterone since it has triple to ten times the potency of testosterone as measured by androgen reception. DHT is made in the following areas of the body: prostate, hair follicles, skin, and testicles. DHT is easier to absorb that testosterone. In short, 5a-reductase is crucial to boosting the male body's DHT levels. DHT causes baldness because hair follicles are very sensitive to DHT. Hair follicles respond to elevated DHT levels by shrinking. As a result, they produce less and less hair or thinner hair. Given sustained and prolonged high levels of DHT, hair follicles stop producing hair. Similarly, high levels of DHT in the prostate can lead to prostate enlargement.

Finasteride binds with 5a-reductase so it doesn't convert as much testosterone into DHT.
Since Finasteride effectively 'mops up' 5a-reductase so there are less of this enzyme in the blood stream, the body's overall levels of DHT drops. Lower DHT levels in the scalp and prostate reduces or even eliminates these tissues' reactions to elevated DHT levels. As mentioned above, the scalp's reaction to DHT is to shrink follicles. The prostate, on the other hand, expands due to increased DHT.

By keeping DHT levels in check, Finasteride enables regular follicle growth and keeps the prostate from enlarging.

Is Buying Propecia (Finasteride) a sure 'cure' for male pattern baldness?

No. This compound handles an enzyme that is responsible for one thirds to two-thirds of the body's production of DHT. Even if Finasteride binds with 5a-reductase completely, there are other enzymes responsible for DHT synthesis and some DHT production is still possible. This is why Finasteride results can vary from the arrest of hair loss to actual hair regrowth.

Is this drug effective against all types of baldness?

No. Finasteride is most effective against balding in the crown region of the scalp and, to a lesser extent, a receding hairline. It produces the best results in the crown.

Do Finasteride's effects persist after treatment is stopped?

No. Finasteride's effects on the scalp and prostate will reverse if Finasteride is stopped. This is expected. After all, this drug doesn't radically transform how DHT is synthesized or how testosterone is metabolized. It only acts as a chemical binder for 5a-reductase so it doesn't convert testosterone into DHT. Once this blocking mechanism stops, the beneficial effects of finasteride are reversed once 5a-reductase starts converting testosterone into DHT once again. The reversal process differs from patient to patient. However, reversal is a certainty since there is no compound blocking 5a-reductase from doing what it normally does.

What are the side effects of Propecia?

Individuals taking this medication can experience erectile dysfunction, irregularities with ejaculation, a lower volume of semen produced during ejaculation, irregular sexual functions or reduced libido, pain in the testicles, and enlarged breasts in males. The good news is that these side effects disappear once patients stop taking finasteride. Another cause for concern regarding this medication is an increased chance of developing high-grade cancer of the prostate. While finasteride is indicated for treating enlarged prostates, the problem is that this compound might prevent early prostate cancer detection. The concern focuses on patients taking this drug to reduce the size of their prostate when the patient actually already developed prostate cancer. Finasteride treatment, in this particular case, delayed earlier diagnosis and treatment. Only when the patient's prostate no longer responds to finasteride would the patient find out that he had developed advanced prostate cancer. One key side effect to look out for when using this medication is its effect on mood. Finasteride's clinical use has been linked with increased levels of anxiety and depression among both male and female users. According to one particular study, a 1mg daily dose of finasteride induced the onset of medium to heavy depression in 83% of the study's participants. Interestingly enough, all females in the study group reported depression. In addition to depression, study participants also reported anxiety. Patients with a high risk or history of depression or anxiety should be very careful when using this medication.See our comprehensive 'Precautions and Warnings' page for a detailed explanation.

Can pregnant women take finasteride?

No. Finasteride is classified by the US Food and Drug Agency in category X or drugs which are known to produce birth defects. Females who may get pregnant or are pregnant must not take this medication. Moreover, they can't even touch or handle broken or crushed finasteride with their bare hands because this compound can be absorbed by the skin. Finasteride is linked to birth defect occurring in male babies.

How was finasteride discovered?

In the mid-70s, a conference presentation by Cornell's Julianne Imperato-McGinley showed a link between lower levels of DHT and 5a-reductase and smaller prostates and the absence of male pattern baldness. Merck's head of research read the presentation notes and went to work on developing a compound that can lower DHT and 5a-reductase in order to treat enlarged prostates. The resulting drug, Finasteride, gained FDA approval for benign prostatic hyperplasia in 1992 and male pattern baldness in 1997.More on Propecia(Finasteride) here.

Summary of Buying Propecia.

Propecia works differently for different people. Fortunately, there are also a large percentage of satisfied users who mainly talk about the great results rather than the side effects. Even if side effects do occur in clinical trials, they have not really taken over every participant. There are still always a good number of participants who have not experienced negative side effects.